HAA-09, an orally administered compound, serves as a powerful anti-influenza agent by targeting the influenza PB2_cap binding domain. It possesses significant activity against influenza A virus, exhibiting an EC50 of 0.03 µM, and demonstrates polymerase inhibition with an IC50 of 0.060.004 µM. Importantly, HAA-09 inhibits virus replication efficiently without inducing noticeable cytotoxicity [1].
Molekulargewicht:
376.36
CAS Nummer:
[1422051-33-9]
Formel:
C17H18F2N6O2
Target-Kategorie:
Virus Protease|||Influenza Virus|||Others
T74806
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