STING-IN-5, a potent inhibitor of the Stimulator of Interferon Genes (STING) pathway, significantly suppresses lipopolysaccharide (LPS)-induced nitric oxide (NO) synthesis in macrophages, exhibiting an IC50 of 1.15 µM. This compound dampens the inflammatory response and offers potential for research into anti-inflammatory diseases and sepsis [1].
Molekulargewicht:
854.17
CAS Nummer:
[2920064-17-9]
Formel:
C47H67NO9S2
Target-Kategorie:
STING
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