Ubiquitination-IN-2 is a potent inhibitor of E1-E2 protein-protein interactions (PPI), exhibiting inhibitory activity with a dissociation constant (Kd) of 0.72 µM for the ubiquitin E1 (Uba1) enzyme. By blocking the transfer of ubiquitin from E1 to E2, Ubiquitination-IN-2 serves as a valuable tool in cancer research [1].
Molekulargewicht:
2346.04
Formel:
C93H173N25O28S8
Target-Kategorie:
E1/E2/E3 Enzyme|||Others
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