JHDM-IN-1 (Compound 1), a Jumonji C domain-containing HDMs (JHDM) inhibitor, exhibits IC50s of 3.4 µM against JMJD2C, 4.3 µM against JMJD2A, 5.9 µM against JMJD2E, 10 µM against PHF8, and 43 µM against JMJD3, showcasing its inhibitory effectiveness across a spectrum of JHDM enzymes [1].
Molekulargewicht:
491.54
CAS Nummer:
[1310809-17-6]
Formel:
C27H29N3O6
Target-Kategorie:
Histone Demethylase|||Others
T75175
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