Compstatin TFA, a potent inhibitor of the complement system C3 characterized by species specificity, is a 13-residue cyclic peptide. It selectively binds to baboon C3 and demonstrates resistance to proteolytic cleavage in baboon blood (similar to humans), effectively inhibiting the activation of the primate complement system. Notably, Compstatin TFA exhibits IC 50 values of 63 µM and 12 µM for the classical and alternative complement pathways, respectively [1] [2] [3].
Molekulargewicht:
1664.79
Formel:
C68H100F3N23O19S2
Target-Kategorie:
Complement System
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