Urotensin I (Catostomus urotensin I) TFA is a CRF-like neuropeptide that acts as an agonist for CRF receptors, with pEC50 values of 11.46 for human CRF1, 9.36 for human CRF2, and 9.85 for rat CRF2alpha receptors in CHO cells. It shows binding affinities (Ki) of 0.4 nM for hCRF1, 1.8 nM for rCRF2alpha, and 5.7 nM for mCRF2beta receptors [1] [2].
Molekulargewicht:
4983.48
Formel:
C212H341F3N62O69S2
Target-Kategorie:
CRFR
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