CCZ01048, an analogue of alpha-melanocyte-stimulating hormone (alpha-MSH), demonstrates a high binding affinity for the melanocortin 1 receptor (MC1R), with a Ki of 0.31 nM. It rapidly internalizes into B16F10 melanoma cells and exhibits notable in vivo stability, making it a promising candidate for PET imaging of malignant melanoma [1].
Molekulargewicht:
1508.72
Formel:
C71H105N21O16
Target-Kategorie:
Melanocortin Receptor
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