PINT-87aa, an 87-amino acid (aa) peptide encoded by the circular form of the long intergenic non-protein-coding RNA p53-induced transcript (LINC-PINT), directly interacts with the polymerase associated factor complex (PAF1c) to inhibit the transcriptional elongation of multiple oncogenes, effectively suppressing glioblastoma cell proliferation both in vitro and in vivo [1].
Molekulargewicht:
9607.03
Formel:
C396H628N140O115S13
Target-Kategorie:
DNA/RNA Synthesis
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