Clervonafusp alfa, CAS [[2145123-44-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: Clervonafusp alfa, CAS [[2145123-44-8]] Preis auf Anfrage
• Artikelnummer: TGM-T77131
• Hersteller Artikelnummer: T77131
• Alternativnummer: TGM-T77131-5MG,TGM-T77131-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen, addressing the mechanisms of Pompe disease. It combines the Fab segment of a cell-penetrating antibody with recombinant human acid alpha-glucosidase (rhGAA). The Fab portion utilizes the nucleoside transporter ENT-2 for cytosolic entry, while rhGAA accesses lysosomes via mannose-6-phosphate receptors (M6PRs). This dual-targeting approach suggests Clervonafusp alfa as a potential therapeutic research candidate for late-onset Pompe disease [1].

Produkteigenschaften

• CAS Nummer: [2145123-44-8]
• Target-Kategorie: glycosidase|||Glucosidase