Saccharopine hydrochloride (L-Saccharopine hydrochloride), an intermediate in lysine degradation and a mitochondrial toxin, is produced through the conversion of lysine and alpha-ketoglutarate by lysine-ketoglutarate reductase. This compound is subsequently oxidized to alpha-aminoapidate semialdehyde and glutamate by saccharopine dehydrogenase, impairing development by disrupting mitochondrial homeostasis [1] [2] [3].
Molekulargewicht:
312.75
Formel:
C11H21ClN2O6
Target-Kategorie:
Endogenous Metabolite|||Others
T77217
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