Ianalumab (VAY-736) is a decarboxylated humanized antibody against BAFF-R that inhibits the interaction between BAFF and BAFF-R, blocking BAFF-mediated apoptosis protection. Ianalumab exhibits antibody-dependent cytotoxicity (ADCC) and activates effector cells via the immune receptor tyrosine activation motif (ITAM).
Reinheit:
>95%
CAS Nummer:
[1929549-92-7]
Target-Kategorie:
TNF|||Others
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