AOH1996, CAS [[2089314-64-5]]

Produktübersicht

• Artikelname: AOH1996, CAS [[2089314-64-5]]
• Artikelnummer: TGM-T77520
• Hersteller Artikelnummer: T77520
• Alternativnummer: TGM-T77520-1MG,TGM-T77520-5MG,TGM-T77520-10MG,TGM-T77520-25MG,TGM-T77520-50MG,TGM-T77520-100MG,TGM-T77520-500MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC). It interferes with the interaction of PCNA with its binding proteins, leading to DNA replication stress and apoptosis. AOH1996 causes proteasome-dependent rpb1 degradation and lethal DNA damage by stabilizing the interaction between PCNA and RNA polymerase II, and acts synergistically with DNA damaging agents to inhibit tumor cell growth.

Produkteigenschaften

• Molekulargewicht: 426.46
• Reinheit: 99.62%
• CAS Nummer: [2089314-64-5]
• Formel: C26H22N2O4
• Target-Kategorie: Apoptosis|||DNA

Bilder

T77520