EN450 is a cysteine-responsive covalent molecular gel degrader of targeted NF-kappaB with antiproliferative and potentially anticancer activity, which acts through a dependence on Cullin E3 ligase and protease, and can be used to study leukemia.
Molekulargewicht:
288.75
Reinheit:
99.72%
CAS Nummer:
[793719-01-4]
Formel:
C11H13ClN2O3S
Target-Kategorie:
Molecular Glues|||NF-kappaB|||E1/E2/E3 Enzyme
T77525
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