ANG1005 is a brain-penetrating peptide-agent conjugate comprising a taxane derivative that features three paclitaxel molecules covalently bonded to Angiopep-2. This design facilitates crossing of the blood-brain and blood-cerebrospinal barriers, with subsequent penetration of malignant cells through the low-density lipoprotein receptor-related protein (LRP1) transport system [1] [2] [3].
Molekulargewicht:
5127.33
CAS Nummer:
[1075214-55-9]
Formel:
C256H306N32O81
Target-Kategorie:
LDLR
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