SPEN-IN-1 (compound X1) is a selective inhibitor of the SPEN protein factor, with a dissociation constant (K d) of 47 nM. It specifically targets RepA, a 431-nucleotide domain within Xist (a non-coding RNA prototype), characterized by 8.5 repeats of a GC-rich motif instrumental in gene silencing [1].
Molekulargewicht:
416.47
Formel:
C27H20N4O
Target-Kategorie:
Others
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