Alsevalimab (FPA-150) is a humanized monoclonal antibody that targets B7-H4. Alsevalimab specifically binds to B7-H4 on the surface of tumor and immune cells, blocking its inhibitory signals on T-cell activation, reversing the immunosuppressive state of the tumor microenvironment, and activating the proliferation and tumor-killing functions of effector T cells. Alsevalimab also mediates ADCC effects, synergistically enhancing antitumor immunity. Alsevalimab is suitable for use in studies of solid tumors.
Reinheit:
98.92%
CAS Nummer:
[2254029-91-7]
Target-Kategorie:
Others
T78287
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