NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-regulation of Wnt signaling proteins. Additionally, it can identify the G9-G10-A11-G12 RNA tetraloop of HIV, thereby obstructing the attachment of the Gag protein to the 5-UTR. This compound demonstrates the potential to impede tumor proliferation and is utilized in the study of Triple-negative breast cancers (TNBCs) [1].
Molekulargewicht:
504.54
CAS Nummer:
[906718-66-9]
Formel:
C29H24N6O3
Target-Kategorie:
HIV Protease|||Others|||Apoptosis|||Bcl-2 Family|||Wnt/beta-catenin
T78579
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