AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 µM, 12.4 µM, and 1.90.08 µM, indicating good in vitro blood-brain barrier (BBB) permeability. It effectively reduces excessive AChE and BuChE levels associated with Alzheimers disease (AD) and holds potential for anti-Alzheimers research [1].
Molekulargewicht:
327.35
Formel:
C19H18FNO3
Target-Kategorie:
Cholinesterase (ChE)|||Others|||Monoamine Oxidase
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