PptT-IN-4 (Compound 3a) is a PptT inhibitor with an IC50 of 0.71 µM, demonstrating antimycobacterial activity against Mtb H37Rv with a MIC of 42 µM. It inhibits hERG, hCav1.2, and hNav1.5 channels with IC50 values of 11 µM, 8.1 µM, and 6.9 µM, respectively [1].
