Dim16 HCl is a dual inhibitor of PCSK9 and HMG-CoA reductase that exhibits an IC50 value of 19 nM for PCSK9, potently blocks PCSK9-LDLR binding with an IC50 of 0.8 nM, and increases LDL uptake in HepG2 cells, supporting its use in lipid metabolism and cardiovascular research.
Molekulargewicht:
620.01
Reinheit:
99.14%
CAS Nummer:
[2743448-41-9]
Formel:
C29H39ClIN5
Target-Kategorie:
Others|||HMG-CoA Reductase
T78718L
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