DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing the expression of CD26, ET-1, FGF-1, and EGF. Additionally, it notably inhibits cancer tissue proliferation in the A549 xenograft mouse model [1].
Molekulargewicht:
427.43
Formel:
C19H17N5O5S
Target-Kategorie:
Others|||DNA/RNA Synthesis
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten