SIKs-IN-1, CAS [[2927557-06-8]]

Produktübersicht

• Artikelname: SIKs-IN-1, CAS [[2927557-06-8]]
• Artikelnummer: TGM-T78762
• Hersteller Artikelnummer: T78762
• Alternativnummer: TGM-T78762-25MG,TGM-T78762-50MG,TGM-T78762-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

SIKs-IN-1 (compound 8h), a pyrimidine-5-carboxamide derivative, functions as an inhibitor of Salt-inducible kinases (SIKs), which play a role in M1/M2 macrophage polarization linked to inflammation. By inhibiting SIK activity, this compound increases anti-inflammatory cytokine IL-10 and decreases pro-inflammatory cytokine IL-12, demonstrating significant anti-inflammatory efficacy in a DSS-induced colitis model [1].

Produkteigenschaften

• Molekulargewicht: 507.58
• CAS Nummer: [2927557-06-8]
• Formel: C27H31F2N7O
• Target-Kategorie: SIK|||Others

Bilder

T78762