SARS-CoV-2-IN-51 (S-10), a lead compound for Omicron fusion inhibition, demonstrates potent activity against Omicron and other SARS-CoV-2 variants, with EC50 values ranging from 0.82-5.45 µM. It functions by directly interacting with the spike (S) protein in the prefusion state [1], thereby preventing viral entry.
Molekulargewicht:
1020.29
Formel:
C58H85NO14
Target-Kategorie:
SARS-CoV
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