Anticancer Agent 157 (compound 15) is a nitric oxide (NO) inhibitor with IC50 values of 0.62 µg/mL, exhibiting both anti-inflammatory and anticancer effects. It interacts with inducible NO synthase (iNOS) and caspase 8, which facilitates apoptosis through nuclear fragmentation and chromatin condensation. Additionally, Anticancer Agent 157 effectively inhibits HT29 colon cancer cells (IC50 =2.45 µg/mL), Hep-G2 liver cancer cells (IC50 =3.25 µg/mL), and B16-F10 murine melanoma cells (IC50 =3.84 µg/mL) [1].
Molekulargewicht:
220.31
Formel:
C14H20O2
Target-Kategorie:
Caspase|||Apoptosis|||NO Synthase
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
