cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 µM for human cGAS and 1.44 µM for mouse cGAS. By inhibiting the abnormal activation of cGAS linked to numerous immune-mediated inflammatory diseases, cGAS-IN-1 possesses potential anti-inflammatory properties [1].
Molekulargewicht:
377.35
CAS Nummer:
[858770-07-7]
Formel:
C18H19NO8
Target-Kategorie:
Others|||cGAS
T78858
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