TWIK-1/TREK-1-IN-1, CAS [[1440532-30-8]]

Produktübersicht

• Artikelname: TWIK-1/TREK-1-IN-1, CAS [[1440532-30-8]]
• Artikelnummer: TGM-T78868
• Hersteller Artikelnummer: T78868
• Alternativnummer: TGM-T78868-25MG,TGM-T78868-50MG,TGM-T78868-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers and TWIK-1/TREK-1 heterodimers, both significant for its role as an antidepressant target. Furthermore, TWIK-1/TREK-1-IN-3, a related compound, selectively inhibits these channels with IC50 values of 9.36 µM for TREK-1 homodimers and 14.6 µM for TWIK-1/TREK-1 heterodimers, demonstrating antidepressant-like effects [1].

Produkteigenschaften

• Molekulargewicht: 395.42
• CAS Nummer: [1440532-30-8]
• Formel: C21H24F3NO3
• Target-Kategorie: Potassium Channel

Bilder

T78868