MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP), promoting MDM2 degradation and impeding XIAP mRNA translation, thereby inhibiting cancer cell proliferation. It exhibits potent activity against the acute lymphoblastic leukemia cell line EU-1, with an IC50 of 0.3 µM [1].
Molekulargewicht:
504.64
CAS Nummer:
[2761969-85-9]
Formel:
C29H32N2O4S
Target-Kategorie:
MDM-2/p53|||Others
T79012
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