(R)-SKBG-1 is an inhibitor of the RNA-binding protein NONO, with an EC50 value of 1.5 µM in 22Rv1 cells. (R)-SKBG-1 reduces mRNA and protein expression of the androgen receptor (AR) and its splice variants (AR-FL and AR-V7), inhibits the proliferation of various cancer cells, and affects the transcriptome and proteome of cancer cells.
Molekulargewicht:
495.98
Reinheit:
97.25%
CAS Nummer:
[2955634-67-8]
Formel:
C22H26ClN3O6S
Target-Kategorie:
MicroRNA|||Androgen Receptor
T79156
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