OATD-02 is an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase 1 and Arginase 2 that exhibits slow dissociation kinetics and nanomolar potency across human and murine arginases, effectively reversing arginase-mediated tumor immunosuppression and enabling mechanistic studies in melanoma immunotherapy research.
Molekulargewicht:
272.15
CAS Nummer:
[2146132-73-0]
Formel:
C12H25BN2O4
Target-Kategorie:
Arginase
T79319
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