A09-003 is a novel cell cycle protein-dependent kinase-9 CDK-9 inhibitor.A09-003 inhibits the proliferation of a variety of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in myeloid cells.A09-003 also induces apoptosis, decreases RNA polymerase II activity, and decreases Mcl-1 expression.
Molekulargewicht:
374.48
Reinheit:
99.84%
CAS Nummer:
[2911646-14-3]
Formel:
C23H26N4O
Target-Kategorie:
Apoptosis|||Bcl-2 Family|||CDK
T79404
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