PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor with an inhibitory constant (Ki) of 53 µM that disrupts the interaction between PEX5 and TbPEX14. It effectively inhibits the bloodstream form of Trypanosoma brucei brucei with a half-maximal effective concentration (EC50) of 5 µM [1].
Molekulargewicht:
444.53
Formel:
C26H28N4O3
Target-Kategorie:
Antibacterial|||Others
T79457
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