Mtb-IN-4 (compound 17h) is a non-toxic isoxazole that exhibits anti-Mycobacterium tuberculosis (Mtb) activity with an IC50 value of 0.70 µM. It impedes Mtb respiration and biofilm formation within macrophages and augments the efficacy of the antibiotic isoniazid (INH) against INH-resistant Mtb mutants [1].
Molekulargewicht:
430.48
CAS Nummer:
[2306039-13-2]
Formel:
C24H18N2O4S
Target-Kategorie:
Others|||Antibacterial
T79559
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