Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 µM, exhibits antioxidant and anti-inflammatory properties by inhibiting oxidative stress-induced cell death and neuroinflammation through the suppression of Keap1, COX-2, and iNOS. It demonstrates low acute toxicity in mice with an LD50 of 1000 mg/kg [1].
Molekulargewicht:
476.43
CAS Nummer:
[2413127-32-7]
Formel:
C21H15F3N4O4S
Target-Kategorie:
COX
T79670
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