Paluratide (LUNA18) is a reversible cyclic peptide KRAS inhibitor with the advantages of oral availability and cell permeability for the treatment of kras-mutant cancers, which inhibits cancer cell proliferation by phosphorylating ERK and AKT, and also inhibits the interaction of RAS with guanine nucleotide exchange factors (GEFs).
Molekulargewicht:
1437.68
Reinheit:
98.70%
CAS Nummer:
[2676177-63-0]
Formel:
C73H105F5N12O12
Target-Kategorie:
ERK|||Akt|||Ras|||Kras
T79673
T79673
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