PI3K-IN-48, a PI3K inhibitor, exhibits an IC50 of 1.55 0.18 µM in A549 cells, demonstrating its potency in this context. It induces G0/G1 phase arrest and cell apoptosis, while also down-regulating the expression of p-PI3K and p-Akt. This compound is relevant for research into the treatment of human lung cancers [1].
Molekulargewicht:
432.44
Formel:
C25H21FN2O4
Target-Kategorie:
Akt|||PI3K
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
