TPH1-IN-1 (compound 40) is a xanthine derivative and inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM. It demonstrates robust in vitro activity and liver microsome stability, effectively impeding the adipocyte differentiation of T3-L1 cells [1].
Molekulargewicht:
450.47
Formel:
C21H18N6O4S
Target-Kategorie:
Others|||Hydroxylase
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