PF-07202954 is a DGAT2 inhibitor with a long half-life. Its IC50 values for human DGAT2 and rat DGAT2 are 10 nM and 9.1-33 nM respectively. It can reduce the triglyceride content in the liver of rats fed with a Western diet and can be used for the study of non-alcoholic fatty liver disease (NASH).
Molekulargewicht:
438.45
Reinheit:
98.99%
CAS Nummer:
[2639372-47-5]
Formel:
C22H23FN6O3
Target-Kategorie:
Transferase
T79764
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