TNG-462 is a potent and selective PRMT5 inhibitor with antitumor activity and oral activity, primarily for the treatment of methylthioadenosine phosphorylase (MTAP)-deficient and/or methylthioadenosine (MTA)-accumulating cancers (e.g., non-small-cell lung cancer, pancreatic cancer, bladder cancer, and hematologic malignancies).
Molekulargewicht:
520.69
Reinheit:
98.70%
CAS Nummer:
[2760483-96-1]
Formel:
C28H36N6O2S
Target-Kategorie:
Histone Methyltransferase
T79873
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