Tubulin polymerization-IN-49 (compound 12d), a potent tubulin polymerization inhibitor that binds to the colchicine site on tubulin, induces cell cycle arrest at the G2/M phase and triggers apoptosis, exhibiting anticancer activity by preventing tumor generation and inhibiting tumor proliferation and angiogenesis [1].
Molekulargewicht:
344.4
Formel:
C20H24O5
Target-Kategorie:
Others|||Microtubule Associated
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