Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with IC50 values of 55 µg/mL and 52 µg/mL, respectively. It exhibits antioxidant properties, effectively inhibiting 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Research suggests feralolides potential in studying cognitive disorders, including Alzheimers disease, for its memory restoration and enhancement capabilities [1].
Molekulargewicht:
344.32
CAS Nummer:
[149418-38-2]
Formel:
C18H16O7
Target-Kategorie:
Cholinesterase (ChE)|||Others
T79963
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