Bid BH3 (80-99), CAS [[505070-05-3]] Preis auf Anfrage
Artikelnummer:
TGM-T80224
Hersteller Artikelnummer:
T80224
Alternativnummer:
TGM-T80224-5MG,TGM-T80224-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Bid BH3 (80-99) is a biologically active peptide and a pro-apoptotic member of the BH3-only (BOPS) subset within the BCL-2 protein family, crucial in apoptosis regulation. It interacts with Bcl-2, Bax, and Bak to initiate their activation or inactivation, inducing cell death. Bid translocates from the cytosol to the mitochondrial membrane as part of its mechanism. Pyroglutamyl (pGlu) peptides, which can arise from Glutamine (Q) or Glutamic acid (E) at the N-terminus, have a hydrophobic gamma-lactam ring that enhances stability and provides resistance to gastrointestinal proteases. These peptides are recognized variants in peptide analyses, including HPLC purity assessments.
Molekulargewicht:
2309.56
CAS Nummer:
[505070-05-3]
Formel:
C95H161N33O32S
Target-Kategorie:
Bcl-2 Family
T80224
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