Lactate Transporter 1 (Compound 1) serves as an active lactate transporter within living cells and exerts cytotoxic effects, exhibiting IC50 values of 3.36 µM in HeLa, 3.27 µM in CAL27, 5.58 µM in MCF7, and 7.66 µM in MCF10A cells. Additionally, an additive effect with Cisplatin has been observed in HeLa cells [1].
Target-Kategorie:
Monocarboxylate transporter
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