DA-PROTAC is a potent degrader of the copper ion-transport proteins Atox1 and CCS, capable of binding to both proteins and facilitating their association with E3 ligase. This interaction enhances the ubiquitination and subsequent proteasomal degradation of Atox1 and CCS. DA-PROTAC is utilized in triple negative breast cancer research [1].
Molekulargewicht:
1010.96
CAS Nummer:
[2488660-12-2]
Formel:
C46H50BrF2N7O8S2
Target-Kategorie:
PROTACs|||Ligands for E3 Ligase
T82610
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