2-O-Methylguanosine-5-O-triphosphate sodium Preis auf Anfrage

Produktübersicht

• Artikelname: 2-O-Methylguanosine-5-O-triphosphate sodium Preis auf Anfrage
• Artikelnummer: TGM-T83819
• Hersteller Artikelnummer: T83819
• Alternativnummer: TGM-T83819-25MG,TGM-T83819-50MG,TGM-T83819-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: 2-methyl GTP , 2-O-methyl GTP

Produktbeschreibung

2-O-Methylguanosine-5-O-triphosphate (2-methyl GTP) acts as an inhibitor targeting the hepatitis C virus (HCV) non-structural protein 5B (NS5B, with an IC50 of 3.5 µM), and serves as an active metabolite of the prodrug IDX184 through a 2-methylguanosine intermediate transformation. Additionally, at a concentration of 50 µM, it promotes tubulin polymerization. Notably, levels of 2-methyl GTP are reduced in the tumoral tissues of patients with hepatocellular carcinoma in comparison to the adjacent normal tissues.

Produkteigenschaften

• Molekulargewicht: 625.13
• Formel: C11H14N5O14P3.4Na
• Target-Kategorie: Others|||Nucleoside Antimetabolite/Analog

Bilder

T83819