BHD, a reversible male contraceptive agent, effectively induces spermatogenic cell apoptosis and causes abnormalities in seminiferous tubules in vivo at doses of 100 and 500 mg/kg. Additionally, it disrupts the blood-testis barrier and decreases the fertility index in male mice, with effects lasting between two to six weeks post-administration.
Molekulargewicht:
411.28
CAS Nummer:
[2749517-98-2]
Formel:
C21H16Cl2N4O
Target-Kategorie:
Others|||Apoptosis
T83870
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