HA-14-1, CAS [[927635-64-1]]

Produktübersicht

• Artikelname: HA-14-1, CAS [[927635-64-1]]
• Artikelnummer: TGM-T84388
• Hersteller Artikelnummer: T84388
• Alternativnummer: TGM-T84388-5MG,TGM-T84388-10MG,TGM-T84388-25MG,TGM-T84388-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

HA-14-1, a small molecule, binds the surface pocket of Bcl-2 proteins (IC50= ~ 9 µM), including Bcl-xl and Bcl-W, and disrupts their interaction with the Bak peptide. This action induces apoptosis by activating Apaf-1 and caspase-9 and -3. Additionally, HA-14-1 effectively induces apoptosis in human acute myeloid leukemia (HL-60) cells, with a 50 µM concentration resulting in a 90% loss of cell viability.

Produkteigenschaften

• Molekulargewicht: 409.2
• CAS Nummer: [927635-64-1]
• Formel: C17H17BrN2O5
• Target-Kategorie: Others|||Bcl-2 Family

Bilder

T84388