()5(6)-DiHET, CAS [[213382-49-1]]

Produktübersicht

• Artikelname: ()5(6)-DiHET, CAS [[213382-49-1]]
• Artikelnummer: TGM-T84609
• Hersteller Artikelnummer: T84609
• Alternativnummer: TGM-T84609-25UG, TGM-T84609-50UG, TGM-T84609-100UG, TGM-T84609-250UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: ()5,6-DiHETrE

Produktbeschreibung

5(6)-DiHET is a racemic compound synthesized through the action of epoxide hydrolases on 5(6)-EET, encompassing both enantiomeric forms. It serves as a quantitative marker for 5(6)-EET, facilitating its measurement by utilizing the compounds conversion to 5(6)-delta-lactone in solution. Additionally, 5(6)-DiHET activates large-conductance calcium-activated potassium (KCa1.1/BK) channels in rat small coronary artery smooth muscle cells, supporting its biological significance in vascular regulation. It also acts as a substrate for sheep seminal vesicle COX, leading to the in vitro production of 5,6-dihydroxy prostaglandin E1 and F1alpha metabolites. Notably, its levels diminish in the plasma of rats subjected to a high-fat diet, indicating a potential role in the pathophysiology of hyperlipidemia.

Produkteigenschaften

• Molekulargewicht: 338.5
• CAS Nummer: [213382-49-1]
• Formel: C20H34O4
• Target-Kategorie: Others