17-phenyl trinor Prostaglandin F2alpha diethyl amide, CAS [[1176637-26-5]] Preis auf Anfrage
Artikelnummer:
TGM-T84653
Hersteller Artikelnummer:
T84653
Alternativnummer:
TGM-T84653-10MG,TGM-T84653-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Alternative Synonym:
Bimatoprost diethyl amide
17-Phenyl trinor Prostaglandin F2alphadiethyl amide (17-phenyl trinor PGF2alphadiethyl amide) is a Prostaglandin F2alpha(PGF2alpha) analog characterized by the substitution of the C-1 carboxyl group with an N-diethyl amide. Prostaglandin (PG) esters and N-ethyl amides have demonstrated ocular hypotensive properties, with N-ethyl amides introduced as alternative options for PG hypotensive prodrugs. Studies indicate that both bovine and human corneal tissues can convert N-ethyl amides of various PGs into their free acid forms at a rate of approximately 2.5 µg/g corneal tissue/hr. However, dialkyl amides like 17-phenyl trinor PGF2alphadiethyl amide resist conversion by corneal amidase, showing no detectable transformation into free acids. This characteristic suggests their potential as valuable investigative tools for assessing the intrinsic intraocular hypotensive activities of PG amides.
Molekulargewicht:
443.6
CAS Nummer:
[1176637-26-5]
Formel:
C27H41NO4
Target-Kategorie:
Prostaglandin Receptor|||Others
T84653
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