BIBO3304 (diTFA), a selective neuropeptide Y (NPY) Y1 receptor antagonist, demonstrates oral efficacy. It exhibits high affinity for Y1 receptors in both humans and rats, with IC50 values of 0.38 nM and 0.72 nM, respectively. Additionally, BIBO3304 (diTFA) enhances bone-tendon healing via the Wnt/beta-catenin signaling pathway [1] [2] [3].
Molekulargewicht:
757.68
CAS Nummer:
[2310085-85-7]
Formel:
C33H37F6N7O7
Target-Kategorie:
Others|||Neuropeptide Y Receptor
T84889
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