CN128, an orally bioavailable iron chelator, features a side chain hydroxy group serving as an alternate sacrificial glucuronidation site to mitigate metabolic inactivation at the 3-hydroxy group. When administered at doses of 150 and 450 µmol/kg, CN128 enhances iron mobilization by 24.8% in a 59Fe-ferritin-loaded rat model of iron overload.
Molekulargewicht:
260.31
CAS Nummer:
[2457170-98-6]
Formel:
C15H18NO3
Target-Kategorie:
Others
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